When vitamin A is readily absorbed from the skin, the skin becomes saturated first and limited quantities of vitamin A also penetrate into the dermis and adipose tissue. A vitamin A deficiency causes hyperkeratinization, resulting in dry, rough skin and atrophy of sebaceous glands and sweat.
Cosmetic properties
Regularization of keratinization
Vitamin A is necessary for proper division of basal cells of the epidermis. It regulates the migration and transformation of keratinocytes into the stratum corneum (top layer of skin). Indeed, it causes a delay of the progressive disappearance of cell nuclei Malpighian characterizes the formation of the stratum corneum. This stimulation of cell renewal decreases epidermal keratinization and has two consequences:
- Thickening of the epidermis
- Thinning of the stratum corneum
These properties of vitamin A can repair damaged skin and dry skin. Moreover, by raising the cellular metabolism, vitamin A improves the condition of skin aging, in which cell renewal is slowed. By preventing the cells of the stratum corneum to accumulate at the pilosebaceous follicle, vitamin A inhibits the formation of blackheads. It can therefore tackle the cons hyperkeratinization, one of the main components of acne.
Changes in the dermis
At the dermal level, vitamin A interferes directly on the metabolism of fibroblasts. Retinol prevents atrophy of the dermis by inhibiting the expression of collagenases and stimulates the synthesis of glycosaminoglycans. A topical treatment with vitamin A increases the elasticity of the skin.
We know further that the UV radiation causes an increase in matrix metalloproteinases, or pretreatment with retinol inhibits the induction and protects the skin damage caused by UV. Thus, application of vitamin A can, prevent the formation of wrinkles caused by UV.
Moreover, UVA exposure leads to a decrease in the vitamin A in the epidermis, but also in the dermis up to 90%. This having trouble returning to normal, it is interesting to make vitamin A topically after sun exposure.
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Tags: Skin Care, UV, UV radiation, UVA, Vitamin, Vitamin A, vitamins for skin care